Team

Computational Biomedicine Group

Francesca Finotello

Group Leader

Research interests: computational analysis of multi-omics data to inform precision and personalized medicine

Lorenzo Merotto

PhD student

Research project: Computational reconstruction of cell trajectories from multi-omics data to advance regenerative medicine and cancer immunotherapy (co-supervisor: Frank Edenhofer, University of Innsbruck)

Irene Rigato

PhD student

Research project: Computational analysis of cancer multiomics data to investigate B-cell malignant transformation

Federico Calabrese

PhD student

Research project: Prediction cancer outcomes with multimodal AI (co-supervisor: Adam Jatowt, University of Innsbruck)

Katharina Huber

Master's student and student assistant

Research project: Investigating the determinants of T-cell expansion in glioblastoma via single-cell RNA sequencing analysis

Constantin Zackl

Master's student

Research project: AI-guided spatial gene prediction from colorectal cancer histology images (co-supervisor: Eva Zangerle, University of Innsbruck)

Felix Petschko

Master's student

Research project: Optimizing speed and scalability of immune cell clonotype clustering for large-scale datasets (co-supervisor: Antonio Rodríguez-Sánchez, University of Innsbruck)

Katharina Schuler

Master's student

Research project: Single-cell informed deconvolution of brain organoids

Esra Baytak

Master's student

Research project: Leveraging the complementarity of omics-based models to predict patients' response to cancer immunotherapy (co-supervisor: Mira Mutschlechner, MCI)

Sebastian Tietz

Lab Rotation student

Research project: Characterization of epithelial-cell programs from breast cancer single-cell RNA-sequencing data

Alumni

  • Markus Ausserhofer: Computational prediction of non-canonical tumor antigens from RNA sequencing data (PhD student; co-supervisor: Frank Edenhofer, University of Innsbruck)
  • Maria Zopoglou: Computational analysis of single-cell RNA sequencing data to quantify dynamic changes in cancer cell regulatory networks during treatment (Master's student)
  • Bernhard Eder: Hierarchical deconvolution of bulk transcriptomics (Master's student; co-supervisor: Philipp Zech, University of Innsbruck)
  • Christina Schwaiger: Prediction and zero correction of gene expression measurements for spatial transcriptomics (Master's student; co-supervisor: Antonio Rodríguez-Sánchez, University of Innsbruck)
  • Luc Wirion: A consensus approach to cell-type deconvolution of bulk transcriptomics informed by multiple single-cell atlases (Bachelor's student)
  • Mario Kanetscheider: Implementation of a Python-based pipeline for the analysis of single-cell B-cell receptor (Bachelor's student; co-supervisor: Mira Mutschlechner, MCI)
  • Franziska Chiara Hörburger: Computational analysis of spatial transcriptomics data to investigate cell-cell colocalization patterns in the tumor microenvironment (Master's student; co-supervisor: Frank Edenhofer, University of Innsbruck)
  • Tobias Ganzenhuber: Improving sequence clustering scalability for adaptive immune cell repertoire analysis (Bachelor's student; co-supervisor: Antonio Rodríguez-Sánchez, University of Innsbruck)
  • Maria Clara Staropoli: Prediction of drug response from tumor RNA sequencing data (Erasmus student; co-supervisor: Chiara Romualdi, University of Padova, Italy)
  • Arianna Zuanazzi: Curation of a single-cell RNA-sequencing atlas of breast cancer (Erasmus student; co-supervisor: Barbara Di Camillo, University of Padova, Italy)
  • Manuel Fiegl: Molecular genetic role of innate system mediated TLR3 signalling in zebrafish cardiac regeneration and proliferation (Master's student; co-supervisor: Dirk Meyer, University of Innsbruck)
  • Max de Rooij: Mathematical modelling of T cell phenotype polarization (Master's student; co-supervisor: Federica Eduati, Eindhoven University of Technology, Netherlands)
  • Silvia Cremon: Computational deconvolution of tumor cellular composition from spatial transcriptomics data (Master's student; co-supervisor: Enrico Lavezzo, University of Padova, Italy)